Online Dictionary

congenital disorder Explained

congenital disorder at English => English (The Britannica Concise) Of Explained:

Structural abnormality (e.g., atresia, agenesis), functional problem (e.g., cystic fibrosis, phenylketonuria), or disease present at birth. Almost all are due to genetic factors (inherited or spontaneous mutations, chromosomal disorders), environmental influences during pregnancy (rubella or other maternal factors, exposure to toxins or radiation), or both. The most sensitive period is the first eight weeks after conception, during which time the human embryo is essentially formed. Major congenital malformations form during this period. Some inherited disorders result from simple Mendelian dominance or recessiveness. Others may involve multiple genes. Chromosomal disorders are rare, because few affected fetuses survive to be born. Environmental influences may affect only one of a pair of identical twins. At least 30 significant defects probably occur per thousand births. Incidence of specific defects varies widely in different racial groups. See also birth defect, Down's syndrome.

congenital disorder at English => English (WordNet) Of Explained:

congenital disorder
n : a defect that is present at birth [syn: {birth defect}, {congenital
anomaly}, {congenital defect}, {congenital abnormality}]